articol-gibelli-2017

ORTHODONTICS
QUANTIFICATION OF DENTAL MOVEMENTS IN ORTHODONTIC FOLLOW-UP:




                                                                                                                                                                                                    Education
A NOVEL APPROACH BASED ON REGISTRATION OF 3D MODELS OF DENTAL CASTS
Daniele Maria Gibelli1a*, Valentina Pucciarelli1b, Luca Pisoni1c, Francesca M.E. Rusconi1d,
Gianluca Martino Tartaglia1e, Chiarella Sforza1f
1
 LAFAS, Laboratory of the Functional Anatomy of the Stomatognathic Apparatus
Department of Biomedical Sciences for Health, University of Milan, Milan, Italy

a
  MD, PhD
b
  BSc
c
  DDS, PhD
d
  MD
e
  DDS, PhD
f
 MD, Head
                                                                                                                                                                     Received: February 28, 2017
                                                                                                                                                                         Revised: March 21, 2017
                                                                                                                                                                        Accepted: April 02, 2017
                                                                                                                                                                        Published: April 03, 2017

Academic Editor: Mariana Păcurar, DDS, PhD, Professor and Head, University of Medicine and Pharmacy Târgu Mureș, Târgu Mureș, Romania

Cite this article:
Gibelli DM, Pucciarelli V, Pisoni L, Rusconi MEF, Tartaglia GM, Sforza C. Quantification of dental movements in orthodontic follow-up:
a novel approach based on registration of 3D models of dental casts. Stoma Edu J. 2017;4(1):53-59.


ABSTRACT                                                                                               DOI: 10.25241/stomaeduj.2017.4(1).art.5
Introduction: The assessment of dental displacement achieved by orthodontic procedures is important
as it allows operators to verify their clinical treatment and provide adequate adjustments. Modern 3D
image acquisition and elaboration systems may represent a valid method for the three-dimensional
assessment of dental movement.
A novel protocol for the 3D assessment of success of orthodontic therapy is proposed, based on
registration of surfaces.
Methdology: Pairs of casts of the upper dental arch, taken at two different time periods during the
therapy, were chosen for three patients who underwent an orthodontic treatment. Dental casts were
scanned by a 3D laser scanner: for each patient, the two 3D models were then registered according to
the least distance at the area including palatal rugae. The chromatic map of changes within the dental
arch and the RMS (Root Mean Square) point-to-point distance between the dental profiles from the two
models were obtained, and compared with the same data from a control group including five adult
individuals who did not undergo orthodontic therapy. Inter- and intra-observer errors were evaluated
as well.
Results: The novel procedure proved to be repeatable and gave a detailed description of those dental
areas most affected by orthodontic therapy: RMS values seem to be related with the weight of dental
modifications and are far higher than the same parameters computed in the control group.
Conclusion: Further studies are needed in order to explore the possible correlation of RMS value with
clinical parameters linked to the improvement of dental function and aesthetics due to orthodontic
therapy.
Keywords: orthodontics, dental anatomy, laser scanner, RMS (root mean square).


1. Introduction                                                                                           During the past century orthodontic techniques
Orthodontics represents one of the most                                                                   have been developed in order to obtain more
sensitive fields of research in dentistry, where                                                          controlled and faster movement of dental
the technological developments and treatment                                                              elements: the main tasks are the improvement
modalities are constantly applied in order                                                                of dental occlusion and function, anatomical
to ameliorate anatomical and functional                                                                   stability and facial aesthetics.1 However, an
characteristics of the dental and facial profile.1                                                        important issue concerns the assessment of


*Corresponding author:
Dr. Daniele Maria Gibelli, MD, PhD, Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, Via Mangiagalli 31, I-20133, Milano, Italy
Tel: +39-02-50315399, Fax: +39-02-50315724, e-mail: daniele.gibelli@unimi.it




Stomatology Edu Journal                                                                                                                                                                               53
            QUANTIFICATION OF DENTAL MOVEMENTS IN ORTHODONTIC FOLLOW-UP:
            A NOVEL APPROACH BASED ON REGISTRATION OF 3D MODELS OF DENTAL CASTS
Education


            Figure 1. 3D model of a dental cast and selection of      Figure 2. Example of registration according to area of
            area including palatal rugae.                             palatal rugae: in white the earlier cast, in light blue the
                                                                      more recent one.

                                                                     This procedure is based on the registration of
                                                                     3D models of casts performed at different times
                                                                     and registration of surfaces according to the least
                                                                     point-to-point distance between the respective
                                                                     surfaces including palatal rugae. Displacement of
                                                                     molars was then assessed according to possible
                                                                     movements of their center of mass as calculated
                                                                     by the software.8 The authors state that the use
                                                                     of laser scanner provides accurate and reliable
                                                                     measurements of dental displacement and
                                                                     might be a valid alternative to cephalometric
                                                                     radiographs.8 However, the potential advantages
                                                                     which may derive from 3D-3D superimposition
                                                                     techniques have still to be explored: for example,
            Figure 3. Example of chromatic map according
                                                                     the previously cited study took only the center
            to point-to-point distance between the two 3D
                                                                     of mass of the tooth into consideration, whereas
            models: blue areas are more vestibularized,
                                                                     techniques of registration may give information
            whereas red and yellow areas are less
                                                                     on the displacement of the entire surface of the
            vestibularized in the last cast than in the first one.
                                                                     dental crown, with a more anatomically adherent
            dental displacement due to orthodontic devices           evaluation of dental arch modifications. In addition,
            for verifying the success of therapy and provide         the assessment of the translation of dental center
            adequate corrections. Most of these procedures           of mass does not take into consideration the entire
            are based on X-ray examinations (OPG or                  range of movements which may affect the 3D dental
            cephalometric radiographs.1-3 In the last years          surface, such as rotation. A possible alternative is
            modern 3D image acquisition systems, already             given by modern 3D image elaboration software,
            applied to the study of facial modifications caused      which are able to provide the registration of 3D
            by dental displacement,4 have been used also to          surfaces and metrical parameters useful to assess
            detect the characteristics of dental movements.          the discordance between two models, expressed
            The main advantage concerns the chance of                in terms of point-to-point mean and RMS (Root
            performing a three-dimensional assessment                Mean Square) distance. In addition, the same
            of dental morphology, more informative than              procedure can generate a chromatic sheet able to
            the traditional radiological methods which are           immediately highlight areas affected by possible
            mainly based on the analysis of displacement             modifications.9,10 These procedures may represent
            of single landmarks or dental two-dimensional            a novel point of view for the assessment of dental
            profile. In addition metrical measurements taken         movements in orthodontic procedures.
            on digital models have been widely tested and            The present article aims at exposing a protocol for
            proved to be reliable, with a high concordance           3D-3D registration of three-dimensional models
            with measurements taken directly on the plaster          of dental casts for the quantification of dental
            models.5-7 However, surprisingly very few studies        displacements, based on the calculation of point-
            have tested 3D image acquisition systems so              to-point distance between two surfaces. This may
            far for assessment of orthodontic therapies: an          provide additional information for evaluating the
            example was provided by Thiruvenkatachari et             success of therapy and orthodontic procedures.
            al. who first developed a protocol for 3D-3D
            superimposition of three-dimensional models of           2. Materials and methods
            dental casts acquired through a laser scanner.8          Casts of the upper dental were chosen from three
                                                                     patients aged from 10 to 15 years who underwent



  54                                                        Stoma Edu J. 2017;4(1):53-59. http://www.stomaeduj.com
                      QUANTIFICATION OF DENTAL MOVEMENTS IN ORTHODONTIC FOLLOW-UP:
                 A NOVEL APPROACH BASED ON REGISTRATION OF 3D MODELS OF DENTAL CASTS




                                                                                                                            Education
 Figure 4. First patient: on the left, the 3D model from the first cast, showing a malposition of both canines; on the
 right, the 3D model from the second cast, after one year and the removal of the second premolar on the right side
 and the first on the left side, and consequent realignment of canines.




Figure 5. first patient, chromatic map of modifications of dental surfaces from the left side between the two casts
(on the left vestibular surface, on the right lingual surface): blue areas are more vestibularized in the last cast, vice
versa for the red and yellow areas. Green areas (including the first and second molar) remained unchanged.



an orthodontic treatment in a private dental office:          RoI. Mean values consider together positive and
all the patients were IOTN (index of orthodontics             negative movements, whereas RMS values are all
treatment needs) ≤3.11 At least two dental casts              positive, and can provide a complete evaluation
were available for each patient, taken at different           of the variations between two dental scans.
time periods during the therapy. The casts were               Together with these quantitative parameters,
scanned by a 3D laser scanner (iSeries, Dental                a chromatic map of surface modifications of
Wings©, Montreal, Canada). According to the                   dental element extracted from the more recent
manufacter, the precision of the instrument is 15             dental cast is provided, with areas coloured in
μm. The 3D models were then elaborated through                blue, green and red: the blue areas are more
VAM© software (Canfield Scientific, Inc., Fairfield,          vestibularized in the last cast than in the earlier
NJ): first the palatal area including palatal rugae           one, whereas the red areas are less vestibularized.
was manually selected in both surfaces (Fig. 1);              Green areas do not show modifications between
then the software was requested to automatically              the two casts (Fig. 3). To test the method on
register the two models in order to reach the                 a control group, the same procedure was
minimum point-to-point distance between the                   applied on the dental arch models of five
selected areas (Fig. 2). Once the registration                adult patients aged over 18 years who had
between the two surfaces was reached, the                     longitudinal records taken but where no dental
dental arch (dental crown surfaces) was manually              movements or modifications were expected.
defined on the 3D model obtained from the                     Time elapsed between the two casts was 1.5 years
more recent cast, and a Region of Interest (RoI)              on average. The same procedures of registration,
was obtained. The software was then requested                 RoI selection, and calculation of RMS values on the
to select the RoI and to calculate the point-to               control group was repeated by the same operator
point mean distance and RMS value (Root Mean                  and by another observer: intra- and inter-observer
Square) of the two models within the selected                 differences were statistically assessed by Student’s



Stomatology Edu Journal                                                                                                       55
            QUANTIFICATION OF DENTAL MOVEMENTS IN ORTHODONTIC FOLLOW-UP:
            A NOVEL APPROACH BASED ON REGISTRATION OF 3D MODELS OF DENTAL CASTS

            Table 1. Details of dental modifications between the two casts in the three analysed patients, and comparison of
Education   correspondent RMS values with the control group.

                                                                                                                   Average point-
                                    First cast                         Second cast                RMS value
                                                                                                                  to-point distance
                                                                     removal of two teeth
                               malposition of 3 teeth
             Patient 1                                            adjustment of malposition         1.61 mm            1.07 mm
                          distal rotation of central incisors
                                                                realignment of central incisors
             Patient 2         malposition of a tooth            adjustment of malposition          1.13 mm            0.24 mm
                          distal rotation of central incisors    correction of central incisors
             Patient 3                                                                              0.98 mm            0.26 mm
                              right canine in eruption               right canine erupted
             Control                                                                                 0.26 mm
                                           -                                   -                                       0.02 mm
             group                                                                                (SD: 0.06 mm)




             Figure 6. Second patient: on the left, the 3D model from the first cast, showing a malposition of the left canine;
             on the right, the 3D model from the second cast, after orthodontic therapy.



                                                                                   The technical error of measurement (TEM) was
                                                                                   respectively 6.1% for intra-observer error and
                                                                                   9.6% for inter-observer error.
                                                                                   The first analysed patient was a female aged 12
                                                                                   years. She had a malposition involving both the
                                                                                   canines and the second premolar on the right
                                                                                   side. The orthodontic treatment was based on the
                                                                                   removal of the second premolar on the right side
                                                                                   and the first on the left side and the application
                                                                                   of an orthodontic device, as shown by the second
                                                                                   cast performed after one year (Fig. 4).
                                                                                   The registration and calculation of point-to-point
                                                                                   distances between the two models highlights
            Figure 7. Second patient. Chromatic map of                             the mesial rotation of the lateral incisors and
            modifications of dental surfaces between the two                       realignment of the canine, whereas the molars did
            casts: blue areas are more vestibularized in the second                not show any appreciable modification (Fig. 5). In
            cast, vice versa for the red and yellow areas. Green                   addition the method was able to verify the novel
            areas remained unchanged.                                              orientation of the second premolar; mean RMS
                                                                                   value between the dental profiles from the two 3D
            t test (p<0.01). In addition the technical error of                    scans amounted up to 1.61 mm.
            measurement (TEM) was evaluated.                                       The second patient, a female aged 11 years,
                                                                                   showed a malposition of the left canine: the
            3. Results                                                             application of an orthodontic device was able to
            In the group of control subjects, on average                           produce an adjustment of the canine position, as
            the RMS value was 0.26 mm (SD: 0.06). No                               shown by the second cast taken after four years
            statistically significant differences were observed                    (Fig. 6).
            between measurements taken by the same                                 The procedures of registration were able to verify
            operator or different observers (p>0.01).                              the vestibular translation of all dental elements,



  56                                                                 Stoma Edu J. 2017;4(1):53-59. http://www.stomaeduj.com
                     QUANTIFICATION OF DENTAL MOVEMENTS IN ORTHODONTIC FOLLOW-UP:
                A NOVEL APPROACH BASED ON REGISTRATION OF 3D MODELS OF DENTAL CASTS




                                                                                                                  Education
 Figure 8. Third patient: on the left, the 3D model from the first cast, showing a malposition of the left
 canine; on the right, the 3D model from the second cast, after orthodontic therapy.


                                                        Interestingly, RMS value increased with the entity
                                                        of dental displacement and number of involved
                                                        teeth, and was in every case significantly higher
                                                        than the same parameter shown by the control
                                                        group (Table 1).

                                                        4. Discussion
                                                        In the last century orthodontics has seen a
                                                        progressive update of technologies and clinical
                                                        procedures, with an amelioration of dental position,
                                                        functionality and aesthetics.1 On the other side, a
                                                        parallel issue concerns the assessment of dental
                                                        displacement powered by orthodontic therapy,
                                                        in order to verify the clinical success and provide
                                                        corrections. Surprisingly, although the constant
Figure 9. Third patient, chromatic map of
                                                        development of 3D image acquisition systems
modifications of dental surfaces between the two
casts: blue areas are more prominent in the last
                                                        has represented a crucial revolution in dentistry,
cast, vice versa for the red and yellow areas. Most     their application to the field of orthodontics is still
of modifications can be observed on the left central    at the beginning and most of their potentiality
incisor and the left canine.                            remains to be explored.8 An example is provided
                                                        by Thirvenkatachari et al. who proposed a
                                                        protocol for the registration of 3D surfaces and
but for the left canine which remained in the same      calculation of displacement of the center of
position and was realigned within the dental            mass of dental elements.8 This type of approach
arch (Fig. 7). In addition, the method was able to      provides a metrical information but is not able
accurate describe the novel presence of brackets        to predict the modifications of the entire dental
and wire in the second cast, correctly assessed in      surfaces, especially where the movements do not
blue areas (more vestibularized in the second cast      consider dental translation. Another important
than in the first one). The average RMS value was       aspect concerns the morphological assessment of
1.13 mm.                                                dental movements, which may give an additional
The third patient was an 11 year old girl, who was      information for the evaluation of orthodontic
chosen in order to test the detectability of lesser     therapies.
dental displacements like pathological overjet          The present protocol may represent a proposal
value. In detail, the central incisors were distally    for an innovative analysis of dental movements:
rotated, whereas the right canine was still erupting    registration is based on the morphology of palatal
with the exposition of the tip. In the second cast,     rugae which are stable with time12,13 and have
after orthodontic therapy, the central incisors were    been already used as reference point in 3D-3D
medially oriented, whereas the canine crown was         superimposition of dental arches.14 The procedure
erupted and in correct occlusion. The second cast       is repeatable and provides both morphological
was taken after four years.                             and metrical analyses of dental movements.
The registration procedure correctly assessed the       The chromatic map of dental arches can give
change in orientation of the left central incisor: in   information concerning the specific movement
addition, the eruption of the canine was detected       of each dental element (rotation, translation or
as well (Fig. 9); RMS value was 0.98 mm.                inclination), immediately readable by the operator.



Stomatology Edu Journal                                                                                             57
            QUANTIFICATION OF DENTAL MOVEMENTS IN ORTHODONTIC FOLLOW-UP:
            A NOVEL APPROACH BASED ON REGISTRATION OF 3D MODELS OF DENTAL CASTS

            On the other side, RMS value provides a reliable                             to the gain in dental function and aesthetics due to
Education   indication concerning the differences between                                orthodontic therapy. This point is crucial, as it may
            the two casts, which seems to be adherent to                                 verify if RMS value in registration of 3D models
            the importance of modifications suffered by                                  of dental cases do represent a potentially useful
            the patients. In addition, patients who were not                             clinical parameter for assessing the success of
            treated from an orthodontic point of view, show                              therapy.
            lower RMS parameters, and this suggests that the
            metrical parameter is strictly linked to the general                         5. Conclusions
            modification of the 3D position of dental crowns.                            In conclusion, a novel protocol for the assessment
            Some      limits   should     be     acknowledged:                           of dental displacement in orthodontic therapy is
            first,   modifications    highlighted      by    the                         proposed: further studies on a large sample of
            registration     procedures        consider     also                         patients may provide additional information about
            dental      eruption,    and       therefore     are                         the clinical advantages which may derive from its
            partly explained by orthodontic therapy.                                     application.
            A possible improvement may consider the
            elaboration of each dental element, in order to                              Acknowledgments
            separately consider already erupted elements.                                The authors declare no conflict of interest related
            Another important limit concerns the possible                                to this study. There are no conflicts of interest and
            correlation of RMS with clinical parameters linked                           no financial interests to be disclosed.
            References
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                                                                                                           Daniele Maria GIBELLI
                                                                                                                 MD, PhD
                                                                        Dipartimento di Scienze Biomediche per la Salute
                                                                                          Università degli Studi di Milano
                                                                                 Via Mangiagalli 31, I-20133, Milano, Italy




            CV
            Daniele Maria Gibelli is a researcher in Human Anatomy in Università degli Studi di Milano (Department of
            Biomedical Sciences for Health). His fields of research are the morphological and metrical assessment of
            anatomical characteristics of bones and teeth, including the anatomical dimorphism, their modification with
            age, ethnic variability and the analysis of individualizing characteristics. He deals also with the analysis of
            facial anatomy both in healthy and pathological conditions, for studies concerning the assessment of facial
            symmetry, modifications with mimicry and anatomical uniqueness of facial structures.



  58                                                                          Stoma Edu J. 2017;4(1):53-59. http://www.stomaeduj.com
                     QUANTIFICATION OF DENTAL MOVEMENTS IN ORTHODONTIC FOLLOW-UP:
                A NOVEL APPROACH BASED ON REGISTRATION OF 3D MODELS OF DENTAL CASTS


Questions




                                                                                      Education
Which instruments can be used to obtain a 3D virtual model of dental arches?
q   a.   Laser scans;
q   b.   Ultrasounds;
q   c.   Conventional orthopantomographs;
q   d.   Bite wing radiographs.

Which kind of modifications can be assessed on 3D virtual model of dental arches?
q   a.   Dental root reabsorption;
q   b.   Parodontal alterations;
q   c.   Dental crown movements;
q   d.   Temporomandibular disorders.

In the current study we assessed
q   a.   Three edentulous patients;
q   b.   Seven patients with deciduous dentition;
q   c.   Two patients submitted to orthognathic surgery;
q   d.   Three adolescent patients.

In the current study, we superimposed 3D virtual models of dental arches using
q   a.   The vestibular surface of anterior teeth;
q   b.   The palatal area including palatal rugae;
q   c.   The lingual surface of mandibular incisors;
q   d.   The occlusal surface of maxillary first molars.




Stomatology Edu Journal                                                                 59