10.25241/stomaeduj.2018.5(1).art.2 – abstract

GERODONTOLOGY

Association between serum resistin level and periodontal condition change among elderly people

DOI: https://doi.org/10.25241/stomaeduj.2018.5(1).art.2

Abstract

Aim: This study aimed to compare periodontal condition in four years of Japanese elderly between high and low serum resistin levels.

Materials and methods: One hundred and thirty-two dentate community-dwelling participants enrolled in this cohort study. At baseline, blood sample were drawn for serum resistin and other adipokines/cytokines measurements. The participants were then divided into 2 groups; low resistin (LR, resistin < 5.3 ng/mL) group (n = 84) and high resistin (HR, resistin ≥ 5.3 ng/mL) group (n = 48). At baseline and after four years, all participants were subjected to periodontal examination (assessment pocket depth; PD and bleeding on probing; BOP). Annual general/oral health questionnaires were also performed. Intergroup comparisons of periodontal parameters and categorical variables were accomplished by t-test and Chi-square test, respectively. Association between baseline serum resistin level and periodontal condition alteration after four years in each group were analyzed by a multiple linear regression analysis.

Results: At baseline, HR group had more sites with PD ≥ 4 mm concomitant BOP than those of LR group (5.8±9.0 vs. 2.8±4.8 sites). High serum resistin concentration and number of tooth loss markedly associated with reduction of sites with PD ≥ 4 mm and PD ≥ 4 mm concomitant BOP.

Conclusion: High serum resistin level might negatively be associated to periodontal disease progression.

Keywords: adipokine, elderly, inflammation, periodontitis, resistin.

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STOMATOLOGY EDU JOURNAL (Stoma Edu J) is a new international dental journal whose main purpose is to inform researchers, educators, graduates, postgraduates and practitioners about the latest trends in the field, which followed, would bring immediate and lasting benefits to the patients; and about opinions of the most authorized specialists on what is best in current practice, for the good of both, patient and dentist.
STOMATOLOGY EDU JOURNAL (Stoma Edu J) is a peer-reviewed, open access international dental journal to be database indexed, meant to contribute to the development and completion of the medical training of practitioners as Dr. Greene Vardiman Black stated: “the professional man has no right to be other than a continual student”.
Open access journal, means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author.